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REVIEW ARTICLE
Year : 2017  |  Volume : 2  |  Issue : 1  |  Page : 3-8

Acute kidney injury following cardiopulmonary bypass surgery


Renal Division, Morehouse School of Medicine, Atlanta, GA, USA

Correspondence Address:
Chamberlain I Obialo
720 Westview Dr SW, Atlanta, GA 30310
USA
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/njct.njct_1_17

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In spite of recent advances in the techniques of cardiopulmonary bypass (CPB), both incidence and mortality rates associated with acute kidney injury (AKI) post CPB remain high. Perioperative risk factors for the AKI include advanced age, diabetes mellitus, underlying kidney disease, and poor cardiac function. Attempts should be made to avoid or modify risk factors such as anemia, preoperative contrast exposure, and excessive hemodilution. The benefits of off-pump coronary artery bypass graft (CABG) surgery on AKI remain equivocal. Well-controlled randomized studies are needed to further clarify the role of various pharmacologic agents such as atrial natriuretic peptides and fenoldopam on the prevention of AKI post-CABG. Continuous renal replacement therapy is preferable to intermittent hemodialysis in patients needing dialysis.


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